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Merobio IV Injection (Meropenem 1gm)
PackSize/
Strength
1000mg ,
Composition

Each vial contains:
Meropenem (as trihydrate) blended with sodium carbonate

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Description

Composition

Meropenem 1000mg Vial

Highlights

1) Meropenem is used to treat a wide variety of stubborn bacterial infections.
2) This medication is known as a carbapenem-type antibiotic.
3) It works by stopping the growth of bacteria, also known as Bactericidal antibiotics.

Description

1) Meropenem is a broad-spectrum carbapenem antibiotic.
2) It is active against Gram-positive and Gram-negative bacteria.
3) Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to bacterial cell death.

Key Features

1) Merobio is manufactured at a dedicated carbapenem plant.
2) State of the art manufacturing under the supervision of highly vigilant staff.
3) Available to patients at a competitive price with superior efficacy.

Dosage and Administration:

Complicated Skin/Skin Structure Infections

Indicated as a single agent therapy for the treatment of complicated skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactiae, viridans group streptococci, Enterococcus faecalis (vancomycin-susceptible isolates only), Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Bacteroides fragilis, and Peptostreptococcus species
500 mg IV q8hr; not to exceed 2 g IV q8hr

Complicated Intra-abdominal Infections

Indicated as a single agent therapy for the treatment of complicated appendicitis and peritonitis caused by viridans group streptococci, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Bacteroides fragilis, B. thetaiotaomicron, and Peptostreptococcus species
1 g IV q8hr; not to exceed 2 g IV q8hr

Community-Acquired Pneumonia

500 mg IV q8hr for ≤5 days

Febrile Neutropenia (Off-label)

1 g IV q8hr

Dosage Modifications

Renal impairment

  1. CrCl >50 mL/min: 0.5-1 g IV q8hr
  2. CrCl 26-50 mL/min: 0.5-1 g IV q12hr
  3. CrCl 10-25 mL/min: 0.25-0.5 g IV q12hr
  4. CrCl <10 mL/min: 0.25-0.5 g IV q24hr

Precautions

Before using meropenem, tell your doctor or pharmacist if you are allergic to it, or to other carbapenems (such as imipenem); or to penicillins or cephalosporins; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.